The Long Dark Diseases, Injuries and Medical Guide

Every illness and injury for beginners: food poisoning, dysentery, parasites, hypothermia, frostbite, sprains, bleeding and infection, with the exact treatment for each.

The Long Dark Diseases, Injuries and Medical Guide
Guide chapters14 chapters

In The Long Dark, injuries and illnesses do not heal by waiting: each one has a specific treatment, and the wrong treatment wastes medicine you cannot replace. Learn the cause, the symptom, and the cure for each condition, and carry the small medical kit that covers all of them: bandages, antiseptic, painkillers, antibiotics, and herbal teas.

Hands warming by a stove — warmth is medicine: hypothermia is treated with heat first.

At a glance

  • Carry always: bandage, antiseptic, painkillers, antibiotics

  • Herbal medicine: reishi tea, rose hip tea, birch bark tea, old man beard dressing

  • Permanent damage: frostbite does not heal

  • Prevention beats cure: cook food, boil water, stay warm and dry

  • Checked: 2026-10-25

Quick answer

  • Bleeding first, always. A bandage stops the Condition drain immediately.

  • Food poisoning comes from raw or ruined food. Antibiotics or reishi tea treat it.

  • Frostbite is permanent. Never let exposed skin stay frozen.

  • Cabin fever comes from too long indoors. Go outside, even briefly, to reset it.

A cabin under mountain peaks — recover indoors: rest only works when you are warm and fed.

1. The first-aid order: bleeding, then everything else

Bleeding is the only condition that drains Condition fast enough to kill you during a walk home, so it is always first. Apply a bandage immediately, and if you have no bandage, improvise from cloth where the game allows. Animal bites also carry infection risk, which is a separate problem: after bandaging, use antiseptic or an old man beard wound dressing to cut that risk. Painkillers do not heal you, but they let an injured survivor move and work, which matters when the nearest bed is a long walk away.

A snowy town at night — pharmacies and houses are where medicine loot spawns.

2. Food poisoning, dysentery, and parasites: the gut trio

Food poisoning comes from eating raw or ruined food. Its symptoms are Condition loss and stomach trouble, and it is treated with antibiotics or reishi mushroom tea, plus rest, food, and water. Dysentery comes from drinking unsafe water, and it is treated with antibiotics or birch bark tea. Intestinal parasites come from eating raw predator meat, and they are treated with antibiotics or reishi tea, but they last longer and drain Condition steadily, which is why predator meat must always be cooked. The prevention for all three is one sentence: cook meat, boil water, and never eat ruined food.

Swipe horizontally to view all columns.

IllnessCauseTreatment

Food poisoning

Raw or ruined food

Antibiotics or reishi tea, rest

Dysentery

Unsafe water

Antibiotics or birch bark tea

Intestinal parasites

Raw predator meat

Antibiotics or reishi tea, long rest

Hypothermia

Prolonged cold exposure

Warmth, fire, warm food and drink

Frostbite

Frozen exposed skin

No cure; prevention only

A gas station under aurora — do not loot for medicine at night in wolf country.

3. Hypothermia and frostbite: cold injuries

Hypothermia happens when your body stays cold for too long: Warmth empties, Condition falls, and you need heat urgently. Treat it with fire, a warm building, warm food and drink, and dry clothes, and do not go back out until Warmth is fully recovered. Frostbite is different and worse: it happens when exposed skin freezes, it causes permanent Condition loss that never heals, and it is the reason clothing coverage matters. Never travel with exposed skin in extreme cold and wind, and if you feel frostbite risk rising, shelter immediately: no loot is worth a permanent penalty.

A ruined shelter in the snow — a sprain far from base means shelter first, treatment second.

4. Sprains, broken ribs, and burns

Sprains come from falls and from struggling on steep ground, and they slow you down and cause pain. Treat a sprain with a bandage and painkillers, and rest it: sprinting on a sprain makes it worse and can strand you. Broken ribs come from bear and moose attacks and from hard falls, and they limit what you can carry and do until they heal with rest and painkillers. Burns come from touching a fire or stove carelessly, and they are treated with a bandage and rest. All three share one rule: an injured survivor should head for base, not push on to the next region.

A snowy road through a valley — an injured survivor walks; do not sprint on a sprain.

5. Cabin fever: the illness of staying inside

Cabin fever is the risk of spending too much consecutive time indoors. Its warning is a growing risk meter, and its result is that you cannot sleep indoors until you spend time outside. The cure is simple and counterintuitive for a game about cold: go outside. Even a short outdoor walk, or time in a cave or a car, resets the risk. Plan long crafting and resting sessions with outdoor breaks built in, especially in late-game runs where you live mostly indoors.

A snowy valley with rock outcrops — cold plus wind plus wet clothes is the frostbite recipe.

6. The medical kit to carry

A travelling medical kit is small: two bandages, antiseptic, painkillers, a course of antibiotics, and a reishi tea and a birch bark tea if you have them. Herbal teas are made from plants you gather, which makes them renewable in a way manufactured medicine is not, so learn the plants in your starting region early. Keep the bulk of your medicine at base, carry the small kit always, and restock the kit every time you return, the same way you restock matches.

Sunset over a pine forest — treat injuries before sunset, not after dark sets in.

7. When to abandon the trip and go home

Abandon the trip when any of these are true: you are bleeding and out of bandages, you have hypothermia and no fire kit, you have a broken rib and a long walk ahead, or you have parasites and no antibiotics or reishi tea. The game rewards the player who goes home sick and returns healthy, and it kills the player who pushes one more region while ill. A sick day at base, with food, water, warmth, and rest, is not a wasted day. It is the reason there are more days.

Sunrise over a frozen lake — a new day after treatment is the real recovery test.

FAQ

Does frostbite ever heal?

No. Frostbite causes permanent Condition loss. Prevention, full clothing coverage and sheltering from wind and cold, is the only answer.

What is the difference between food poisoning and dysentery?

Food poisoning comes from raw or ruined food; dysentery comes from unsafe water. They share symptoms but need different herbal teas: reishi for poisoning, birch bark for dysentery, while antibiotics treat both.

Can I sleep off an illness?

Rest helps, but most illnesses need their specific treatment as well. Sleep without treatment for parasites or dysentery just burns food and water while Condition keeps falling.